Hair Regeneration Protocol with A.P.A.G. + Medifuge

A Regenerative Approach to Hair Loss Using PRP and CGF

A Regenerative Approach to Hair Loss Using PRP and CGFThe A.P.A.G. system, when combined with the Medifuge centrifuge, offers a powerful protocol for hair regeneration using autologous blood derivatives such as PRP (Platelet-Rich Plasma), PPP (Platelet-Poor Plasma), and CGF (Concentrated Growth Factors).
This protocol stimulates hair regrowth, slows miniaturization, and strengthens hair follicles — all with minimally invasive, biocompatible techniques.
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PRP Application Technique

• Method: Retrogressive technique (injection from frontal to occipital region)
• Instruments: 3-way multiple injector with 27G x 4 mm needles
• Delivery: Via mesotherapy, microinjection, or irrigation​

​Protocol Timeline

A 6-session treatment cycle is performed, with each session spaced 21 days apart:

1. Session 1- Initial Treatment
2. Session 2 – Hair loss stabilizes
3. Session 3 – Miniaturization begins to reverse
   4–6. Maintenance and consolidation of results

⏱ Visible improvement:
Between 6 to 12 months, patients begin to notice global changes, including increased hair density and thickness.
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Results – Microscopic and Clinical Evidence

Miniaturization Reversal
Dermatoscopic evaluation shows a clear reduction in hair miniaturization after only 2 months post-third PRP session (PRP03), with regrowth of thicker, more pigmented shafts.
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Before

2 months after_PRP=03

Clinical Case: First Cycle PRP O3 – 2012/2013

Photographic follow-up shows progressive improvement in a patient undergoing a PRP protocol from October 2012 to January 2013:

• October 06, 2012 – Baseline: significant thinning
  
• December 07, 2012 – Mid-cycle: density begins to improve
  
• January 12, 2013 – 4 months: visibly denser and fuller hair
  

6 October 2013

7 December 2012

12 January 2013 _ 4 months